Campylobacter Research Today is a free monthly online journal that collates and summarizes the latest research about Campylobacter, including details on food poisoning, infection, symptoms, treatment.

Isolation and expression of a novel molecular class D beta-lactamase, OXA-61, from Campylobacter jejuni.

Alfredson DA, Korolik V

Microbial Glycobiology, Institute for Glycomics, Griffith University and Microbiology Department, Queensland Health Pathology Services, Gold Coast Hospital, 108 Nerang St., Southport, Queensland, Australia 4215. David_Alfredson@health.qld.gov.au

A novel beta-lactamase gene, blaOXA-61, from Campylobacter jejuni GC015 was cloned and its nucleotide sequence determined. blaOXA-61 encodes a protein of 257 amino acids in which the active-site STFK tetrad and conserved class D beta-lactamase motifs YGN and KTG were identified. A conserved sequence upstream of blaOXA-61 is required for expression in Campylobacter.

Published 26 May 2005 in Antimicrob Agents Chemother, 49(6): 2515-8.
Full-text of this article is available online (may require subscription).

© 2004-2008 Campylobacter Research Today. All Rights Reserved.